Journal: Hearing research

Article Title: Cochlear implant material effects on inflammatory cell function and foreign body response

doi: 10.1016/j.heares.2022.108597

Figure Lengend Snippet: Intracochlear neo-ossification relative to platinum and PDMS bearing surfaces. 3D X-ray microscopy images of a single chronically implanted mouse cochlea (A,B,C) with the CI imaged in-situ were volumetrically segmented to compare the amount of neo-ossification in 3 separate areas: the area immediately adjacent to platinum electrode surfaces “Electrode” (red), the area adjacent to PDMS surfaces toward the backside of the electrode contact surface “Anti-electrode” (green), and the intracochlear portions basal to the E1 electrode “Non-electrode” (blue). Dashed lines in (A) denote the manual separation of the “Electrode” (red) and “Anti-electrode” (green) areas in which neo-ossification was volumetrically quantified and in (B,C) indicate the basal and apical limits confining the “Electrode” and “Anti-electrode” areas, with the “Non-electrode” area being basal to this area, stopping at the round window. “E1”, “E2” and “E3” denotes electrode contacts 1,2 and 3, respectively; “M” denotes modiolus; “RW” denotes the round window outlined by a red hashed circle in (B,C). The gray and dark yellow shading in (B) represent the open scala tympani space and areas of soft tissue fibrosis without neo-ossification, respectively. Mean quantification of volume of neo-ossification across n = 6 subjects with individual data points noted as dots and error bars representing 1 standard deviation is shown in (D). The greatest volume of neo-ossification was seen in the “Electrode” area immediately adjacent to the Platinum electrodes, followed by the “Anti-electrode” and “Non-electrode” areas, however these differences were not significant (p > 0.05).

Article Snippet: 3D X-ray microscopy data were analyzed in GraphPad Prism software (Graph-Pad Software, USA) via ordinary one-way ANOVA.

Techniques: Microscopy, In Situ, Standard Deviation

Journal: BMC Infectious Diseases

Article Title: Diagnostic performance of smear microscopy and incremental yield of Xpert in detection of pulmonary tuberculosis in Rwanda

doi: 10.1186/s12879-016-2009-x

Figure Lengend Snippet: Flow chart showing series of participants’ recruitment and the outcome of different tuberculosis testing methods used. +: Positive, - : Negative, AFB: Acid Fast Bacilli, PTB: Pulmonary tuberculosis, ZN Lab: Ziehl Nelsen health facility laboratories-, LED-FM Lab: Light emitting diode-fluorescence microscopy using health facility laboratories, NTM: Non-tuberculous Mycobacteria, cont.: contaminated

Article Snippet: Based on quality control of smear microscopy (QC) data of 2012 and 2013 these eight laboratories performed equally well, though the QC for intermediate is performed by the NRL whereas QC for peripheral are subsequently done by ILs.

Techniques: Fluorescence, Microscopy

Journal: BMC Infectious Diseases

Article Title: Diagnostic performance of smear microscopy and incremental yield of Xpert in detection of pulmonary tuberculosis in Rwanda

doi: 10.1186/s12879-016-2009-x

Figure Lengend Snippet: Yield of smear microscopy versus Xpert among culture confirmed tuberculosis patients ( n =96)

Article Snippet: Based on quality control of smear microscopy (QC) data of 2012 and 2013 these eight laboratories performed equally well, though the QC for intermediate is performed by the NRL whereas QC for peripheral are subsequently done by ILs.

Techniques: Microscopy